431+ Rental Villas and Private Getaways in Main Street Hyannis |
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Main Street Hyannis Vacation Rentals & One Degree Stays Homes

About Main Street Hyannis Vacation Rentals

There are more than 431 vacation rentals that are available in Main Street Hyannis. These rentals, including vacation rentals, One Degree Stays Homes (ODSs) and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at an ODS property in Main Street Hyannis.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With OneDegreeStays Main Street Hyannis, you have the flexibility of comparing different options of various deals with a single click. Looking for an ODS with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner (ODSs), and other popular Airbnb-style properties in Main Street Hyannis. Places to stay near Main Street Hyannis are 1103.39 ft² on average, with prices averaging US $500 a night.

OneDegreeStays makes it easy and safe to find and compare vacation rentals in Main Street Hyannis with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

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Top Rental Accommodation Types in Main Street Hyannis

Type Count
Vacation Homes 280
Holiday Apartments 35
Cottages 23
Villas 1

Use these Quick Filters to Find a Vacation Rental in Main Street Hyannis

★ Pro Tip: OneDegreeStays makes it easy to compare the best listings on ODS homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between ODS homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Main Street Hyannis.

Weather in Main Street Hyannis, MA

View the weather forecast for Main Street Hyannis before booking your Main Street Hyannis Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Top Attractions Around Main Street Hyannis, MA

OneDegreeStays offers a large selection of top attractions around Main Street Hyannis. Research things to do on your vacation before you visit Main Street Hyannis.


John F. Kennedy Hyannis Museum
Cape Cod Baseball Hall of Fame
Cape Cod Carousel
Wackenhammer's Clockwork Arcade
Cape Codder Water Park
Harwich Port
Hyannis Harbor
Old Silver Beach
Nauset Beach
Mayflower Beach
West Dennis Beach
Seagull Beach
Sandy Neck Beach
Hyannis Port Beach
Falmouth Heights Beach
Massachusetts Maritime Academy
Craigville Beach
Sandwich Boardwalk
Cape Cod Inflatable Park
Sandwich Glass Museum

Other Places to Stay in Main Street Hyannis, MA


Cape Cod Baseball Hall of Fame 1,355 Properties
John F. Kennedy Hyannis Museum 1,351 Properties
Cape Cod Carousel 1,342 Properties
Wackenhammer's Clockwork Arcade 1,336 Properties
Hyannis 369 Properties

Frequently Asked Questions About Main Street Hyannis?

What are the top vacation rentals in Main Street Hyannis?

There are a lot of options in Main Street Hyannis. If you plan on staying in the Main Street Hyannis area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Main Street Hyannis:

How many vacation rentals have private pools in Main Street Hyannis?

There are 26 vacation rentals with private pools near Main Street Hyannis. Top-rated ODS homes that have access to a swimming pool include:

Which vacation homes in Main Street Hyannis are best for families?

If you are looking for a family-friendly vacation home in Main Street Hyannis, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Main Street Hyannis:

How many onedegreestays vacation rentals are available in Main Street Hyannis?

Currently, the total number of properties listed by One Degree Stays in 2025 is over 431 in the Main Street Hyannis area, and still counting. By aggregating listings from multiple websites, One Degree Stays offers an immense amount of choice of the best ODS properties in Main Street Hyannis. 


People Also Ask

There are 431 Main Street Hyannis, MA Vacation Rentals

Recently Booked Vacation Rentals in Main Street Hyannis