471+ Rental Villas and Private Getaways in Uptown |
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Uptown Vacation Rentals & One Degree Stays Homes

About Uptown Vacation Rentals

There are more than 471 vacation rentals that are available in Uptown. These rentals, including vacation rentals, One Degree Stays Homes (ODSs) and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at an ODS property in Uptown.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With OneDegreeStays Uptown, you have the flexibility of comparing different options of various deals with a single click. Looking for an ODS with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner (ODSs), and other popular Airbnb-style properties in Uptown. Places to stay near Uptown are 798.4 ftยฒ on average, with prices averaging $262 a night.

OneDegreeStays makes it easy and safe to find and compare vacation rentals in Uptown with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

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Top Rental Accommodation Types in Uptown

Type Count
Vacation Homes 331
Cottages 52
Holiday Apartments 36

Use these Quick Filters to Find a Vacation Rental in Uptown

โ˜… Pro Tip: OneDegreeStays makes it easy to compare the best listings on ODS homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between ODS homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Uptown.

Weather in Uptown, SC

View the weather forecast for Uptown before booking your Uptown Vacation Rentals to confirm your best time to go.

December - February
High 60ยฐF       Low 26ยฐF
March - May
High 77ยฐF       Low 40ยฐF
June - August
High 91ยฐF       Low 64ยฐF
September - November
High 84ยฐF       Low 38ยฐF

Frequently Asked Questions About Uptown?

What are the top vacation rentals in Uptown?

There are a lot of options in Uptown. If you plan on staying in the Uptown area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Uptown:

How many vacation rentals have private pools in Uptown?

There are 4 vacation rentals with private pools near Uptown. Top-rated ODS homes that have access to a swimming pool include:

Which vacation homes in Uptown are best for families?

If you are looking for a family-friendly vacation home in Uptown, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Uptown:

How many onedegreestays vacation rentals are available in Uptown?

Currently, the total number of properties listed by One Degree Stays in 2025 is over 471 in the Uptown area, and still counting. By aggregating listings from multiple websites, One Degree Stays offers an immense amount of choice of the best ODS properties in Uptown.โ€ฏ

Nearby Neighborhood (5)โ€ฏ
Neighborhood Property Count
Historic District Vacation Rentals in Beaufort, South Carolina 362
The Old Commons Vacation Rentals in Beaufort, South Carolina 58
Pigeon Point Vacation Rentals in Beaufort, South Carolina 37
The Point Vacation Rentals in Beaufort, South Carolina 29
Northwest Quadrant Vacation Rentals in Beaufort, South Carolina 27

People Also Ask

There are 471 Uptown, SC Vacation Rentals

Recently Booked Vacation Rentals in Uptown