153+ Rental Villas and Private Getaways in Depew |
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Depew Vacation Rentals & One Degree Stays Homes

About Depew Vacation Rentals

There are more than 153 vacation rentals that are available in Depew. These rentals, including vacation rentals, One Degree Stays Homes (ODSs) and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at an ODS property in Depew.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With OneDegreeStays Depew, you have the flexibility of comparing different options of various deals with a single click. Looking for an ODS with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner (ODSs), and other popular Airbnb-style properties in Depew. Places to stay near Depew are 420.89 ft² on average, with prices averaging US $213 a night.

OneDegreeStays makes it easy and safe to find and compare vacation rentals in Depew with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

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Top Rental Accommodation Types in Depew

Type Count
Vacation Homes 63
Holiday Apartments 26
Cottages 1
Villas 1

Use these Quick Filters to Find a Vacation Rental in Depew

★ Pro Tip: OneDegreeStays makes it easy to compare the best listings on ODS homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between ODS homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Depew.

Weather in Depew, NY

View the weather forecast for Depew before booking your Depew Vacation Rentals to confirm your best time to go.

December - February
High 60°F       Low 26°F
March - May
High 77°F       Low 40°F
June - August
High 91°F       Low 64°F
September - November
High 84°F       Low 38°F

Top Attractions Around Depew, NY

OneDegreeStays offers a large selection of top attractions around Depew. Research things to do on your vacation before you visit Depew.


KeyBank Center
Walden Galleria Mall
New Era Field
University At Buffalo - North Campus
Buffalo Niagara Convention Center
Fashion Outlets of Niagara Falls
Canalside
Six Flags Darien Lake
Buffalo State College
Buffalo Zoo
University at Buffalo - South Campus
Shea's Performing Arts Center
Buffalo Museum of Science
Sahlen Field
Roswell Park Cancer Institute
Peace Bridge
Delaware Park
Buffalo City Hall
Buffalo and Erie County Botanical Gardens
Canisius College

Frequently Asked Questions About Depew?

What are the top vacation rentals in Depew?

There are a lot of options in Depew. If you plan on staying in the Depew area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Depew:

How many vacation rentals have private pools in Depew?

There are 4 vacation rentals with private pools near Depew. Top-rated ODS homes that have access to a swimming pool include:

Which vacation homes in Depew are best for families?

If you are looking for a family-friendly vacation home in Depew, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Depew:

How many onedegreestays vacation rentals are available in Depew?

Currently, the total number of properties listed by One Degree Stays in 2025 is over 153 in the Depew area, and still counting. By aggregating listings from multiple websites, One Degree Stays offers an immense amount of choice of the best ODS properties in Depew. 


People Also Ask

There are 153 Depew, NY Vacation Rentals

Recently Booked Vacation Rentals in Depew