58+ Rental Villas and Private Getaways in Lake Nona |
  1. USA
  2. Florida
  3. Orlando
  4. Lake Nona

Lake Nona Vacation Rentals & One Degree Stays Homes

About Lake Nona Vacation Rentals

There are more than 58 vacation rentals that are available in Lake Nona. These rentals, including vacation rentals, One Degree Stays Homes (ODSs) and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at an ODS property in Lake Nona.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With OneDegreeStays Lake Nona, you have the flexibility of comparing different options of various deals with a single click. Looking for an ODS with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner (ODSs), and other popular Airbnb-style properties in Lake Nona. Places to stay near Lake Nona are 393.07 ftยฒ on average, with prices averaging $208 a night.

OneDegreeStays makes it easy and safe to find and compare vacation rentals in Lake Nona with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Show more
Show less

Top Rental Accommodation Types in Lake Nona

Type Count
Holiday Apartments 26
Vacation Homes 7

Use these Quick Filters to Find a Vacation Rental in Lake Nona

โ˜… Pro Tip: OneDegreeStays makes it easy to compare the best listings on ODS homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between ODS homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Lake Nona.

Weather in Lake Nona, FL

View the weather forecast for Lake Nona before booking your Lake Nona Vacation Rentals to confirm your best time to go.

December - February
High 60ยฐF       Low 26ยฐF
March - May
High 77ยฐF       Low 40ยฐF
June - August
High 91ยฐF       Low 64ยฐF
September - November
High 84ยฐF       Low 38ยฐF

Other Places to Stay in Lake Nona, FL


Sanford-Burnham Medical Research Institute 102 Properties
University of Central Florida College of Medicine 73 Properties
Lake Nona Medical City 52 Properties
VA Medical Center at Lake Nona 52 Properties
Nemours Children's Hospital 50 Properties
David Leadbetter Golf Academy 35 Properties
Waters Edge Community 30 Properties

Frequently Asked Questions About Lake Nona?

What are the top vacation rentals in Lake Nona?

There are a lot of options in Lake Nona. If you plan on staying in the Lake Nona area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Lake Nona:

Which vacation homes in Lake Nona are best for families?

If you are looking for a family-friendly vacation home in Lake Nona, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Lake Nona:

How many onedegreestays vacation rentals are available in Lake Nona?

Currently, the total number of properties listed by One Degree Stays in 2025 is over 58 in the Lake Nona area, and still counting. By aggregating listings from multiple websites, One Degree Stays offers an immense amount of choice of the best ODS properties in Lake Nona.โ€ฏ

Nearby Neighborhood (4)โ€ฏ
Neighborhood Property Count
Southeast Orlando Vacation Rentals in Orlando, Florida 253
Lake Nona Medical City Vacation Rentals in Orlando, Florida 52
Waters Edge Community Vacation Rentals in Orlando, Florida 30
LaVina Vacation Rentals in Orlando, Florida 27

People Also Ask

There are 58 Lake Nona, FL Vacation Rentals

Recently Booked Vacation Rentals in Lake Nona