346+ Rental Villas and Private Getaways in Mayo Clinic |
  1. USA
  2. Arizona
  3. Phoenix
  4. Mayo Clinic

Mayo Clinic Vacation Rentals & One Degree Stays Homes

About Mayo Clinic Vacation Rentals

There are more than 346 vacation rentals that are available in Mayo Clinic. These rentals, including vacation rentals, One Degree Stays Homes (ODSs) and other short-term private accommodations, have top-notch amenities with the best value, providing you with comfort and luxury at the same time. Get more value and more room when you stay at an ODS property in Mayo Clinic.

Looking for last-minute deals, or finding the best deals available for cottages, condos, private villas, and large vacation homes? With OneDegreeStays Mayo Clinic, you have the flexibility of comparing different options of various deals with a single click. Looking for an ODS with the best swimming pools, hot tubs, allows pets, or even those with huge master suite bedrooms and have large screen televisions? You can find vacation rentals by owner (ODSs), and other popular Airbnb-style properties in Mayo Clinic. Places to stay near Mayo Clinic are 2131.82 ftยฒ on average, with prices averaging US $520 a night.

OneDegreeStays makes it easy and safe to find and compare vacation rentals in Mayo Clinic with prices often at a 30-40% discount versus the price of a hotel. Just search for your destination and secure your reservation today.

Show more
Show less

Top Rental Accommodation Types in Mayo Clinic

Type Count
Vacation Homes 237
Holiday Apartments 39
Villas 10

Use these Quick Filters to Find a Vacation Rental in Mayo Clinic

โ˜… Pro Tip: OneDegreeStays makes it easy to compare the best listings on ODS homes from online vacation rental OTAs, including Booking.com and more. Use the Advanced Filter feature at the top to easily flip between ODS homes, vacation rentals, bed and breakfasts, private Airbnb-style rentals availability, eco-friendly properties, property type, cancellation policies, prices, and several different options. All these make it easier to find the perfect accommodation for your next vacation in Mayo Clinic.

Weather in Mayo Clinic, AZ

View the weather forecast for Mayo Clinic before booking your Mayo Clinic Vacation Rentals to confirm your best time to go.

December - February
High 60ยฐF       Low 26ยฐF
March - May
High 77ยฐF       Low 40ยฐF
June - August
High 91ยฐF       Low 64ยฐF
September - November
High 84ยฐF       Low 38ยฐF

Other Places to Stay in Mayo Clinic, AZ


Mayo Clinic Scottsdale 360 Properties

Frequently Asked Questions About Mayo Clinic?

What are the top vacation rentals in Mayo Clinic?

There are a lot of options in Mayo Clinic. If you plan on staying in the Mayo Clinic area, consider making a reservation for a few nights at one of these properties as these have been rated the Top Vacation Rentals in Mayo Clinic:

How many vacation rentals have private pools in Mayo Clinic?

There are 122 vacation rentals with private pools near Mayo Clinic. Top-rated ODS homes that have access to a swimming pool include:

Which vacation homes in Mayo Clinic are best for families?

If you are looking for a family-friendly vacation home in Mayo Clinic, check out one of the following properties as all are highly-rated places to stay with excellent review for families or groups staying in Mayo Clinic:

How many onedegreestays vacation rentals are available in Mayo Clinic?

Currently, the total number of properties listed by One Degree Stays in 2025 is over 346 in the Mayo Clinic area, and still counting. By aggregating listings from multiple websites, One Degree Stays offers an immense amount of choice of the best ODS properties in Mayo Clinic.โ€ฏ

Nearby Neighborhood (1)โ€ฏ
Neighborhood Property Count
Central Scottsdale Vacation Rentals in Phoenix, Arizona 702

People Also Ask

There are 346 Mayo Clinic, AZ Vacation Rentals

Recently Booked Vacation Rentals in Mayo Clinic